Anti tumor
Pyrimidinetetramine sulfat (5392-28-9)
Pyrimidinetetramine sulfate is used as intermediate of Methotrexate. Product Name: Pyrimidinetetramine sulfate CAS No.: 5392-28-9 Assay: 98% End Use: Methotrexate Molecular Formula: C4H10N6O4S Molecular Weight: 238.22 Shelf Life: 2 Years Package: 25kg/drum
Metotreksat (59-05-2)
Methotrexate is a drug used for the treatment of cancer, also known as cytotoxic drugs. In order to reduce its cytotoxicity, it can be used in conjunction with calcium leucovorin. It is primarily used for the treatment of acute leukemia (acute lymphocytic leukemia), breast cancer, malignant mole and choriocarcinoma, head and neck cancer, bone cancer, leukemia, spinal cord meningeal infiltration, lung cancer, reproductive system cancer, liver cancer, refractory psoriasis
2,6-Dioxopiperidine-3-ammonium klorida (24666-56-6)
2,6-Dioxopiperidine-3-ammonium chloride is a reagent for preparing lenalidomide. It can also be used to prepare phthalimide conjugates. Product Name: 2,6-Dioxopiperidine-3-ammonium chloride CAS No.: 24666-56-6 Assay: 98% End Use: Pomalidomide Molecular Formula: C5H9ClN2O2 Molecular Weight: 164.59 Shelf Life: 2 Years Package: 25kg/drum
Pomalidomide (19171-19-8)
Pomalidomide is is a kind of antitumor drugs for the treatment of multiple myeloma. It has many functions such as anti-tumor, immune regulation and anti-angiogenesis. Product Name: Pomalidomide CAS No.: 19171-19-8 Assay: 98% Specification: CP, EP, In-house, as required Molecular Formula: C13H11N3O4 Molecular Weight: 273.24 Shelf Life: 2 Years Package: 25kg/drum
6- (((Bromomethyl)-2,4-pteridinediamin hydrobromide (52853-40-4)
6-(Bromomethyl)-2,4-pteridinediamine hydrobromide is a potent inhibitor of the enzyme nitroaldolase (EC 1.2.1.22) and has been shown to inhibit cell growth in murine leukemia cells. It is an intermediate of Pralatrexate. Product Name: 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide CAS No.: 52853-40-4 Assay: 98% End Use: Pralatrexate Molecular Formula: C7H8Br2N6 Molecular Weight: 335.99 Shelf Life: 2 Years Package: 25kg/drum
Pralatrexate (52853-40-4)
Pralatrexate, an injectable DHFR inhibitor, was launched for the treatment of patients with relapsed or refractory PTCL. The inhibition of the folate enzymes DHFR and thymidylate synthase is a well-validated method of cancer treatment. Product Name: Pralatrexate CAS No.: 52853-40-4 Assay: 989% Specification: CP, EP, In-house, as required Molecular Formula: C23H23N7O5 Molecular Weight: 477.47 Shelf Life: 2 Years Package: 25kg/drum
Raltitrexed (112887-68-0)
Raltitrexed is an anti-tumor drug for advanced colorectal cancer. Raltitrexed is a highly selective inhibitor of thymidylate synthase (TS), the key enzyme in the biochemical conversion of dUMP to dTMP. It enters the cell via the reduced folatefmethotrexate cell membrane carrier and is converted to the polyglutamate species by folylpolyglutamate synthase within 4h where it then binds to the folate substrate site of TS. Product Name: Raltitrexed CAS No.: 112887-68-0 Assay: 99%
6-Bromomethyl-3,4-dihydro-2-methyl-quinazolin-4-one (112888-43-4)
6-Bromomethyl-3,4-dihydro-2-methyl-quinazolin-4-one is an intermediate of Raltitrexed. Product Name: 6-Bromomethyl-3,4-dihydro-2-methyl-quinazolin-4-one CAS No.: 112888-43-4 Assay: 98% End Use: Raltitrexed Molecular Formula: C10H9BrN2O Molecular Weight: 253.1 Shelf Life: 2 Years Package: 25kg/drum
5-[N-(tert-butoxycarbonyl) -N-methylamino]-2-thiophenecarboxylic acid (131052-68-1)
5-[N-(tert-butoxycarbonyl)-N-methylamino]-2-thiophenecarboxylic acid is used as intermediate of Raltitrexed. Product Name: 5-[N-(tert-butoxycarbonyl)-N-methylamino]-2-thiophenecarboxylic acid CAS No.: 131052-68-1 Assay: 98% End Use: Raltitrexed Molecular Formula: C11H15NO4S Molecular Weight: 257.3 Shelf Life: 2 Years Package: 25kg/drum
5-Nitrothiophene-2-carboxylicacid (6317-37-9)
5-Nitrothiophene-2-carboxylicacid is an intermediate of Raltitrexed Product Name: 5-Nitrothiophene-2-carboxylicacid CAS No.: 6317-37-9 Assay: 98% End Use: Raltitrexed Molecular Formula: C5H3NO4S Molecular Weight: 173.15 Shelf Life: 2 Years Package: 25kg/drum
Relugolix (737789-87-6)
Relugolix is a highly selective, oral, nonpeptide GnRH antagonist being investigated as a possible prostate cancer treatment. Product Name: Relugolix CAS No.: 737789-87-6 Assay: 99% Specification: CP, EP, In-house, as required Molecular Formula: C29H27F2N7O5S Molecular Weight: 623.63 Shelf Life: 2 Years Package: 25kg/drum
Ruxolitinib Fosfat (1092939-17-7)
Ruxolitinib is an anti-tumor drug for the treatment of myeloproliferative neoplasm-associated myelofibrosis, further myeloproliferative neoplasms, polycythemia vera and refractory cancer. Product Name: Ruxolitinib Phosphate CAS No.: 1092939-17-7 Assay: 98% Specification: CP, EP, In-house, as required Molecular Formula: C17H21N6O4P Molecular Weight: 404.36 Shelf Life: 2 Years Package: 25kg/drum
4-kloro-7-((2-(trimethylsilyl)ethoxy) methyl)-7H-pyrrolo[2,3-d]pyrimidine (941685-26-3)
4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine is used in the design and preparation of ruxolitinib. Product Name: 4-chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine CAS No.: 941685-26-3 Assay: 98% End Use: Ruxolitinib Molecular Formula: C12H18ClN3OSi Molecular Weight: 283.83 Shelf Life: 2 Years Package: 25kg/drum
3-siklopentylacrylonitrile (591769-05-0)
3-Cyclopentylacrylonitrile and its derivatives are used in the preparation of ruxolitinib intermediates and trasitinib phosphate. Product Name: 3-cyclopentylacrylonitrile CAS No.: 591769-05-0 Assay: 98% End Use: 591769-05-0 Molecular Formula: C9H12 Molecular Weight: 120.19 Shelf Life: 2 Years Package: 25kg/drum
(R) -tert-butyl 3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate (1022150-11-3)
(R)-tert-Butyl 3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate is a key intermediate of Ibrutinib. Product Name: (R)-tert-Butyl 3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate CAS No.: 1022150-11-3 Assay: 98% End Use: Ibrutinib Molecular Formula: C27H30N6O3 Molecular Weight: 486.57 Shelf Life: 2 Years Package: 25kg/drum
6-(6-(trifluoromethyl)pyridin-2-yl)-1,3,5-triazine-2,4 ((1H,3H) -dione (1446507-38-5)
6-(6-(trifluoromethyl)pyridin-2-yl)-1,3,5-triazine-2,4(1H,3H)-dione is an intermediate of Enasidenib mesylate. Product Name: 6-(6-(trifluoromethyl)pyridin-2-yl)-1,3,5-triazine-2,4(1H,3H)-dione CAS No.: 1446507-38-5 Assay: 98% End Use: Enasidenib mesylate Molecular Formula: C9H5F3N4O2 Molecular Weight: 258.16 Shelf Life: 2 Years Package: 25kg/drum
4-Amino-2-trifluorometilpiridin (147149-98-2)
4-Amino-2-trifluoromethylpyridine is an intermediate of Enasidenib mesylate. Product Name: 4-Amino-2-trifluoromethylpyridine CAS No.: 147149-98-2 Assay: 98% End Use: Enasidenib mesylate Molecular Formula: C6H5F3N2 Molecular Weight: 162.11 Shelf Life: 2 Years Package: 25kg/drum
5-aMino-3-(4-fenoxyphenyl)-1H-pyrazole-4-carbonitrile (330792-70-6)
5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile is a key intermediate of Ibrutinib. Product Name: 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile CAS No.: 330792-70-6 Assay: 98% End Use: Ibrutinib Molecular Formula: C16H12N4O Molecular Weight: 276.29 Shelf Life: 2 Years Package: 25kg/drum
Ibrutinib (936563-96-1)
Ibrutinib is a non-receptor Bruton's tyrosine kinase inhibitor approved for the treatment of relapsed chronic lymphocytic leukemia(CLL), mantle cell lymphoma (MCL) and WaldenstrÖm's Macroglobulinemia (WM). Product Name: Ibrutinib CAS No.: 936563-96-1 Assay: 98% Specification: CP, EP, In-house, as required Molecular Formula: C25H24N6O2 Molecular Weight: 440.5 Shelf Life: 2 Years Package: 25kg/drum
5- ((4-fenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine (330786-24-8)
5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine (330786-24-8) is a key intermediate of Ibrutinib. Product Name: 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine CAS No.: 330786-24-8 Assay: 98% End Use: Ibrutinib Molecular Formula: C17H13N5O Molecular Weight: 303.32 Shelf Life: 2 Years Package: 25kg/drum
(S)-1-Boc-3-hidroksipiperidin (143900-44-1)
(S)-1-Boc-3-hydroxypiperidine is a key intermediate of Ibrutinib. Product Name: (S)-1-Boc-3-hydroxypiperidine CAS No.: 143900-44-1 Assay: 98% End Use: Ibrutinib Molecular Formula: C10H19NO3 Molecular Weight: 201.26 Shelf Life: 2 Years Package: 25kg/drum
