Raltitrexed (112887-68-0)
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Product:
Raltitrexed
Description:
CAS:112887-68-0; anti-tumor ; thymidylate synthase; polyglutamate species
Category:
Anti-Tumor
In-stock:
In Stock
Payment Method:
L/C, T/T
Shipping Method:
AIR, Express
Specifications
CAS:
112887-68-0
Specification:
CP, EP, As Required
M.F.:
C21H22N4O6S
M.W.:
458.49
Assay:
98%
Shelf Life:
2 Years
Package:
25kg/drum
High Light:
Raltitrexed 112887-68-0
,thymidylate synthase 112887-68-0
,polyglutamate species 112887-68-0
Introduction
Raltitrexed is an anti-tumor drug for advanced colorectal cancer. Raltitrexed is a highly selective inhibitor of thymidylate synthase (TS), the key enzyme in the biochemical conversion of dUMP to dTMP. It enters the cell via the reduced folatefmethotrexate cell membrane carrier and is converted to the polyglutamate species by folylpolyglutamate synthase within 4h where it then binds to the folate substrate site of TS.
| Product Name: | Raltitrexed |
| CAS No.: | 112887-68-0 |
| Assay: | 99% |
| Specification: | CP, EP, In-house, as required |
| Molecular Formula: | C21H22N4O6S |
| Molecular Weight: | 458.49 |
| Shelf Life: | 2 Years |
| Package: | 25kg/drum |
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5-Nitrothiophene-2-carboxylicacid (6317-37-9) |
CAS: 6317-37-9; anti-tumor ; thymidylate synthase; polyglutamate species
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